Need access to NeoLink? Contact your Sales rep or our Client Services team at 866.776.5907, Option 3

August 13, 2025

FISH

Reminder: The AML Standard Panel and MDS Standard Panel have been updated to better align with current guidelines, including WHO 2022 5th Edition Classification, and to facilitate more effective disease management for AML and MDS. Please ensure to include the Reflex option in your orders for complete assessment of your patients’ disease.

AML Standard FISH Panel

• Main panel: MLL (11q23) | RUNX1/RUNX1T1 (ETO/AML1) t(8;21) | PML/RARA t(15;17) | CBFB inv(16), t(16;16) | RPN1, MECOM (3q21, 3q26.2)
• Optional Reflex panel: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | DEK/NUP214 (CAN) t(6;9) | p53 (17p13.1)/NF1 (17q11) | NUP98 (11p15), when the main panel is negative.
• Reflex results are reported separately as AML Standard Reflex Panel.
• CPT Codes*: 88374x5 automated. If reflex is added, add 88374x5.

MDS Standard FISH Panel

• Main panel: 5q-, -5 (5p15, 5q31, 5q33) | 7q-, -7 (Cen 7, 7q22, 7q31) | Trisomy 8 (Cen 8) | 20q- (20q12, 20qter) | p53 (17p13.1)/NF1 (17q11) | RPN1, MECOM (3q21, 3q26.2). Note: +8 and 20q- are combined.
• Optional Reflex panel: ETV6 (12p13) | MLL (11q23) | +19 (19p13.2, 19q13), when the main panel is negative.
• Reflex results are reported separately as MDS Standard Reflex Panel.
• CPT Codes*: 88374x5 automated. If reflex is added, add 88374x3.

Please download or order the latest Heme requisition forms for complete ordering options. Interface clients: Please update your test compendium with the Reflex options.

For more information, please contact your local NeoGenomics sales representative or our Client Services team at 1-866-776-5907, option 3.